Minister Michael Mahendere was born on 28 May 1983. He grew up in a family of seven children, with him being the fourth child. His brothers are Akim, Misheck, and Amos, among the other siblings and their parents are devout Christians who always taught their children Christian morals which Michael Mahendere commends them for.

Michael Mahendere married Vimbai Nyatsambo on December 2011. Vimbai works alongside Michael Mahendere in his work and is the co-manager of his band, Direct Worship. They are well known for their powerful collaborations such as Zvichanaka from Getting Personal with God 2 and also Masimba from Getting Personal with God III. The two have four children together.